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Annals of Dermatology 2011 May; 23(2): 193~197
Annals of Dermatology 2011 May; 23(2): 193~197

A Case of Fibroelastolytic Papulosis on the Neck of a Young Man
Young Chan Song, M.D., Byung Ho Oh, M.D., Jong Hyun Ko, M.D., Ji Young Kim, M.D., Young Ji Hwang, M.D., Yang Won Lee, M.D., Yong Beom Choe, M.D., Kyu Joong Ahn, M.D., Kyae Yong Song, M.D.1
Department of Dermatology, Konkuk University School of Medicine, Seoul, 1Department of Pathology, ChungAng University School of Medicine, ChungAng University Medical Center, Seoul, Korea
This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Fibroelastolytic papulosis of the neck (FEPN) encompasses a spectrum of two disorders that were previously reported as pseudoxanthoma elasticum-like papillary dermal elastolysis (PXE-PDE) and white fibrous papulosis of the neck (WFPN). The clinical presentation of FEPN is asymptomatic to mildly pruritic whitish-yellow papules that may coalesce into cobblestone patterned plaques that resemble pseudoxanthoma elasticum (PXE). The histology is characterized by a decrease or loss of elastic fibers in the papillary dermis and this is sometimes accompanied by a minimal or nodular increase of dermal collagen fibers. We report here on a 28-year-old Korean man with asymptomatic, multiple, skin-colored to slightly yellowish, match-head sized, cobblestone-patterned papules on the neck, and these were histologically consistent with FEPN and the papules showed slightly increased dermal collagen associated with decreased and fragmented elastic fibers, elastin and tropoelastin. The pathogenesis of FEPN in this case might have been related with mild dermal inflammation, followed by fragmentation, elastolysis and increased dermal collagen. (Ann Dermatol 23(2) 193∼197, 2011)
Annals of Dermatology 2011 May; 23(2): 193~197
Keyword : Elastolysis, Fibroelastolytic papulosis
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